Reviewed by Peptide Treatments Medical Advisory Board (Medical Advisory Board)

MK-677: Evidence Summary

Evidence summary for MK-677 across studied indications. Each indication is graded using our evidence tier system based on the quality and quantity of available clinical data.

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Indication Evidence Tier Trial Count Summary
Growth hormone secretion Tier B 6 Consistently raises GH and IGF-1 levels to youthful ranges in clinical trials
Muscle wasting / sarcopenia Tier C 3 Improved lean mass in elderly subjects but mixed functional outcomes
Sleep quality Tier C 2 Increased REM and stage IV sleep duration in healthy volunteers